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Tocris Bioscience™ MR 24

Tocris Bioscience™ MR 24

Ref: p-200086946
177.10€ - 625.25€

Potent and selective MST3 kinase binding inhibitor

Nom chimique ou matériau:
8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
Cible:
Other Kinase Inhibitors
Formule moléculaire:
C<sub>26</sub>H<sub>29</sub>ClN<sub>6</sub>O<sub>3</sub>.3HCl
Pureté:
0.98
Brand
Tocris Bioscience&trade;
Référence Prix Marque Quantité Add to cart
30067264 177.10€ - 625.25€ Tocris Bioscience™ 50 mg
30067255 177.10€ - 625.25€ Tocris Bioscience™ 10 mg
MR 24 is a potent and selective MST3 kinase binding inhibitor with >10 fold selectivity over MST4 (EC50 values from NanoBRET assay are 57 nM and 583 nM for MST3 and MST4 respectively). MR 24 increases the number of cells in G1 phase of cell cycle, is non-cytotoxic and cell permeable. Shows 90% stability over 1 hour in activated liver microsomes in vivo.

Nom chimique ou matériau : 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride

Cible : Other Kinase Inhibitors

Formule moléculaire : C26H29ClN6O3.3HCl

Pureté : 0.98

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