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R&D Systems™ Human VHL (NP_000542) VersaClone cDNA

Réf. : BL-RE-100181Réf. fabricant : 18735638 10 μg
294,81 € HT

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

Expression
hVHL
Numéro d’adhésion
NP_000542
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
655 bp
Marque
R&D Systems

Caractéristiques principales

  • Also known as: RCA1; VHL1; pVHL; HRCA1
  • Von Hippel Lindau, VHL, is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity.
  • VHL is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF).
  • RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of VHL.
  • VHL is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors.
  • Alternatively spliced transcripts encoding different proteins have been described.
  • The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
  • For reasearch use only. Not for use in humans.

Caractéristiques techniques

MarqueR&D Systems
Réf. B-LABOBL-RE-100181
Réf. fabricant18735638
Expression<i>h</i>VHL
Numéro d’adhésionNP_000542
Concentration10 μg at 0.2 μg/μL
FormulecDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert655 bp
Identification génétique (Entrez)7428
Contenu et stockageStore the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
EspècesHuman
Quantité10 μg
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