This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.
IFN-alpha/beta R1, also known as IFNAR1, is a 120 kDa component of the class II cytokine receptor that contributes to the functional receptor for type I IFNs
IFN-alpha/beta R1 associates with the 100 kDa IFN-alpha/beta R2 component to form a receptor complex that transmits anti-viral and anti-proliferative signals
Down-regulation of the receptor is accomplished by ubiquitination and degradation
Binding and activation of IFNAR1 stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. It also functions as an antiviral factor
The IFN-alpha/beta R1 insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided
For reasearch use only. Not for use in humans.
Caractéristiques techniques
Marque
R&D Systems
Réf. B-LABO
BL-RE-109047
Réf. fabricant
18757858
Expression
<i>cyno</i>IFNAR1
Numéro d’adhésion
EHH61907
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
1693 bp
Identification génétique (Entrez)
3454
Contenu et stockage
Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Espèces
Cynomolgus Monkey
Quantité
10 μg
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