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Invitrogen™ Human MRP2 Vesicles | B-LABO France
Invitrogen™ Human MRP2 Vesicles
Réf. : BL-RE-109554Réf. fabricant : 10252500 0.5 mL
976,00 € HT
Human MRP2 Vesicles are insect derived purified plasma membranes that carry MRP2 transport protein (multidrug resistance-associated protein, ABCC2). The ATP-binding cassette transporter carries organic anions and can be used to evaluate test compounds and drug interactions with in in vitro assays.
Forme physique
Frozen
Quantité
0.5 mL
Pureté
Research Grade
Espèces hôtes
Human
Contenu et stockage
Store at -80°C.
Marque
Invitrogen
Points forts
Use Human MRP2 Vesicles to
Concept Behind ABC Transporter VesiclesABC transporter vesicles are easy-to-use, efficient reagents for early assessment of a drug candidate 's substrate and drug interaction potential. While ABC transporters typically mediate the export of substrates out of cells, transporters expressed on these inside-out vesicles import substrates into the vesicles. It is therefore possible to quantitatively evaluate transport activity for your compound by determining the amount incorporated into the vesicles.
Clear and Reliable ResultsPrepared from Sf9 cells which have been engineered to over-express specific ABC transporters, these inside-out vesicles provide high levels of transporter activity with low background, giving you a clear signal if your compound is a substrate or inhibitor of a specific efflux transporter.
Investigate the transporter interactions of your drug candidates
Assess potential for transporter-mediated drug-drug interactions
Obtain high quality results with a large signal to noise ratios
Caractéristiques techniques
Marque
Invitrogen
Réf. B-LABO
BL-RE-109554
Réf. fabricant
10252500
Forme physique
Frozen
Quantité
0.5 mL
Pureté
Research Grade
Espèces hôtes
Human
Contenu et stockage
Store at -80°C.
Format
Vial
Conditions d’expédition
Dry Ice
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