Na+/K+ ATPase modulator; antihypertensive agent
Rostafuroxin is a Na+/K+ ATPase modulator. Inhibits the Normalizes renal Na+/K+ ATPase pump function in mutant adducin- and endogenous ouabain-dependent forms of hypertension. Reduces blood pressure in Milan hypertensive rats. Controls mania-like behaviors in
Myshkin
mice having a Na+/K+ ATPase α3 subunit mutation. Antagonizes the effects of Ouabain (Cat.No. 1076) on myogenic tone and Ca2+ signaling in rat hippocampal neurons.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-124730 |
| Réf. fabricant | 18795319 |
| Nom chimique ou matériau | 3β,5β,14β)-21,23-Epoxy-24-norchola-20,22-diene-3,14,17-triol |
| CAS | 156722-18-8 |
| Synonyme | PST 2238 |
| Quantité | 50 mg |
| Cible | Na+/K+ ATPase Modulators |
| Formule moléculaire | C<sub>23</sub>H<sub>34</sub>O<sub>4</sub> |
| Poids de la formule | 374.51 |
| Pureté | >98% |
