Reagent for RNA SHAPE-MaP experiments in vivo; cell permeable
NAI is a reagent for RNA SHAPE-MaP experiments in live cells. Acylates the 2'-OH in RNA, labels single stranded or flexible regions more than folded regions (SHAPE methodology). Enables analysis of RNA secondary structures at single nucleotide resolution. Exhibits greater signals with lower background than 1M7 for
measurement of the RNA structurome. Also more stable than 1M7 in water. β-mercaptoethanol terminates reaction. Cell permeable.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-124758 |
| Réf. fabricant | 18729706 |
| Nom chimique ou matériau | 1 H-Imidazol-1-yl(2-methyl-3-pyridinyl)methanone |
| CAS | 1055970-47-2 |
| Quantité | 10 mg |
| Cible | DNA, RNA and Protein Synthesis Compounds |
| Formule moléculaire | C<sub>10</sub>H<sub>9</sub>N<sub>3</sub>O |
| Poids de la formule | 2424 |
