IA-Alkyne is a broad spectrum cysteine reactive probe. Covalently binds cysteine residues in proteins. Can be utilized for covalent fragment-based ligand discovery (FBLD) and to identify Zn2+-binding cysteines. Used as a click-chemistry handle to attach a fluorophore or biotin to reactive cysteines in proteins for visualization by in-gel fluorescence or identification by mass spectrometry, respectively. Covalently binds cysteine residues in and activates TRPA1 channels.
Caractéristiques techniques
| Marque | Tocris |
| Réf. B-LABO | BL-RE-124848 |
| Réf. fabricant | 18777296 |
| Nom chimique ou matériau | N-5-Hexyn-1-yl-2-iodoacetamide |
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| CAS | 930800-38-7 |
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| Quantité | 5 mg |
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| Cible | General Laboratory Research Reagent |
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| Formule moléculaire | C<sub>8</sub>H<sub>12</sub>INO |
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| Poids de la formule | 1919 |
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| Pureté | 97% |
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