"/> Tocris Bioscience™ Hh-Ag1.5 | B-LABO France

Tocris Bioscience™ Hh-Ag1.5

Réf. : BL-RE-125011Réf. fabricant : 18758716 5 mg
705,17 € HT

Potent and high affinity Smo receptor agonist

Nom chimique ou matériau
3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
CAS
612542-14-0
Quantité
5 mg
Cible
Smoothened
Formule moléculaire
C28H26ClF2N3OS
Marque
Tocris Bioscience

Hh-Ag1.5 is a potent and high affinity Hedgehog (Hh) receptor agonist (EC50 = 1 nM; Ki values are 0.5 and 2.3 nM respectively, in a [3H]SAG-1.3 and [3H]Cyclopamine binding assay). It is used in protocols for the chemical reprogramming of mouse embryonic fibroblasts into neural stem cells. Also induces differentiation of hiPSCs into skin-derived precursor cells, spinal motor neurons and spinal sensory neurons.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-125011
Réf. fabricant18758716
Nom chimique ou matériau3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
CAS612542-14-0
Quantité5 mg
CibleSmoothened
Formule moléculaireC<sub>28</sub>H<sub>26</sub>ClF<sub>2</sub>N<sub>3</sub>OS
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