"/> Tocris Bioscience™ GSK 2795039 | B-LABO France

Tocris Bioscience™ GSK 2795039

Réf. : BL-RE-125187Réf. fabricant : 18737566 5 mg
170,62 € HT

NADPH oxidase 2 (NOX2) inhibitor

Nom chimique ou matériau
N-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide
CAS
1415925-18-6
Quantité
5 mg
Cible
NADPH Oxidase Inhibitors
Formule moléculaire
C23H26N6O2S
Marque
Tocris Bioscience

GSK 2795039 is a NADPH oxidase 2 (NOX2) inhibitor (pIC50 value is 5.5 to 6.5, depending on assay performed), which displays selectivity for NOX2 other NOX isoforms, xanthine oxidase and eNOS. GSK 2795039 inhibits reactive oxygen species (ROS) in cellular assays, and displays efficacy in rodent models of paw inflammation and acute pancreatitis.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-125187
Réf. fabricant18737566
Nom chimique ou matériauN-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide
CAS1415925-18-6
Quantité5 mg
CibleNADPH Oxidase Inhibitors
Formule moléculaireC<sub>23</sub>H<sub>26</sub>N<sub>6</sub>O<sub>2</sub>S
Pureté0.98
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