AMG PERK 44 is a potent and selective PERK inhibitor (IC50 = 6 nM). Exhibits >160-fold selectivity for PERK over B-Raf and GCN2, as well as a panel of 387 other kinases. Orally bioavailable.
- Nom chimique ou matériau
- 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
- CAS
- 1883548-84-2
- Quantité
- 50 mg
- Cible
- PERK Inhibitors
- Formule moléculaire
- C34H28N4O2.HCl
- Poids de la formule
- 561.07
- Pureté
- >98%
