G 28UCM is a FASN inhibitor. Inhibits breast cancer cell proliferation in vitro (IC50 values are 21 - 79 μM), including cell lines resistant to anti-HER2 therapies. Blocks HER2 signaling and induces apoptosis. Inhibits growth of breast cancer xenografts in mice without causing anorexia.
- Nom chimique ou matériau
- 3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate
- CAS
- 1094451-90-7
- Quantité
- 10 mg
- Cible
- Fatty Acid Synthase Inhibitors
- Formule moléculaire
- C24H16O10
- Poids de la formule
- 464.38
- Pureté
- >98%
