SGC AAK1 1 is an adaptor-associated protein kinase 1 (AAK1) and BMP-2-inducible protein kinase (BMP2K) inhibitor (IC50 values are 233 nM and 1.48 μM for AAK1 and BMP2K, respectively). Inhibits AAK1-dependent phosphorylation of AP2M1. Activates Wnt signaling.
- Nom chimique ou matériau
- N-(6-(3-((N,N-diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide
- CAS
- 2247894-32-0
- Quantité
- 5 mg
- Formule moléculaire
- C21H25N5O3S
- Poids de la formule
- 427.52
- Pureté
- 98%
