Rac inhibitor
EHop 016 is a Rac inhibitor (IC50 = 1.1 μM). Exhibits some selectivity for Rac1 and Rac3 over Cdc42. Blocks the interaction of Rac with guanine nucleotide exchange factor Vav2 in breast cancer cell lines expressing high levels of Rac activity and inhibits activity of Rac downstream effector PAK1. Also inhibits mammary tumor growth and metastasis in mice.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-125337 |
| Réf. fabricant | 18709786 |
| Nom chimique ou matériau | Rho GTPase Inhibitors |
| CAS | 1380432-32-5 |
| Plage de pourcentage du dosage | >98% |
| Quantité | 5 mg |
| Formule moléculaire | C<sub>25</sub>H<sub>30</sub>N<sub>6</sub>O |
| Poids de la formule | Observed MW: 430.55 |
