Highly potent FLT3 inhibitor
Quizartinib is a highly potent FMS-like receptor tyrosine kinase-3 (FLT3) inhibitor (Kd = 1.6 nM, IC50 = 0.56 nM in MV4-11 cell proliferation assay). Displays >10-fold selectivity for FLT3 over panel of 400 kinases. Inhibits FLT3 activity and displays antitumor properties in a mouse MV4-11 tumor xenograft model.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-125452 |
| Réf. fabricant | 18739546 |
| Quantité | 10 mg |
| Formule moléculaire | C<sub>29</sub>H<sub>32</sub>N<sub>6</sub>O<sub>4</sub>S |
| Poids de la formule | 560.67 |
| Type de produit | Inhibitor |
| Pureté | 98% |
