NGI 1 is an oligosaccharyltransferase (OST) inhibitor; anti-flaviviral. Inhibits dengue, Zika, West Nile, and yellow fever viruses by blocking viral RNA replication (EC50 values are 0.85 and 2.2 μM for DENV and ZIKV inhibition, respectively). Selectively arrests proliferation of non-small-cell lung cancer cells that are dependent on EGFR or FGFR for survival.
- Nom chimique ou matériau
- 5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)benzamide
- CAS
- 790702-57-7
- Quantité
- 25 mg
- Cible
- Other Transferase Inhibitors
- Formule moléculaire
- C17H22N4O3S2
- Poids de la formule
- 394.51
- Pureté
- 98%
