"/> Tocris Bioscience™ JQEZ5 | B-LABO France

Tocris Bioscience™ JQEZ5

Name: Tocris Bioscience™ JQEZ5
Brand: Tocris Bioscience
SKU: 18769686
Price: 714.88 EUR
Availability: InStock

Réf. : BL-RE-125631Réf. fabricant : 18769686 50 mg

714,88 € HT

Potent and selective SAM-competitive EZH2 inhibitor

Nom chimique ou matériau: N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
CAS: 1913252-04-6
Quantité: 50 mg
Formule moléculaire: C₃₀H₃₈N₈O₂
Pureté: 98%
Marque: Tocris Bioscience

JQEZ5 is a potent and selective SAM-competitive EZH2 lysine methyltransferase inhibitor (IC50 = 11 nM). Selectively binds EZH2 over a panel of 22 methyltransferases. Reduces global level of the PRC2-associated mark H3K27me3 in K562 cells. Suppresses cell growth in CML cells. Inhibits colony formation of primary human CD34+ CML stem/ progenitor cells. Antitumor effects

in vivo

Caractéristiques techniques

Marque	Tocris Bioscience
Réf. B-LABO	BL-RE-125631
Réf. fabricant	18769686
Nom chimique ou matériau	N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
CAS	1913252-04-6
Quantité	50 mg
Formule moléculaire	C<sub>30</sub>H<sub>38</sub>N<sub>8</sub>O<sub>2</sub>
Pureté	98%

Une question, une configuration particulière ?
Contactez-nous pour un devis.

Demander un devis 03 65 67 15 79

Tocris Bioscience™ JQEZ5

Caractéristiques techniques

Produits similaires

Tocris Bioscience™ BAY 805

Tocris Bioscience™ BAY 805

Tocris Bioscience™ RNB 61

Tocris Bioscience™ IBG3