Functionalized cereblon ligand for PROTAC development
PD 4'-oxyacetic is a carboxylic acid-functionalized cereblon ligand that can be used for PROTAC® Degrader development. The compound can be used to develop PD-PROTACs that exhibit improved stability and potency compared with PROTACs synthesized using IMiD (immunomodulatory imide drug) analogs.
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-125779 |
| Réf. fabricant | 18775856 |
| Nom chimique ou matériau | 2-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenoxy]acetic acid |
| CAS | 2633633-12-0 |
| Quantité | 50 mg |
| Cible | Degrader Building Blocks |
| Formule moléculaire | C<sub>12</sub>H<sub>12</sub>N<sub>2</sub>O<sub>5</sub> |
