"/> Tocris Bioscience™ aTAG 4531 | B-LABO France

Tocris Bioscience™ aTAG 4531

Réf. : BL-RE-125962Réf. fabricant : 18779786 5 mg
491,35 € HT

Degrader of MTH1 fusion proteins for use within the aTAG system

Nom chimique ou matériau
N-Cyclopropyl-6-(4-((4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)methyl)-1 H-1,2,3-triazol-1-yl)butyl)carbamoyl)-3-fluorophenyl)-7-fluoro-4-(phenylamino)quinoline-3-carboxamide
CAS
2412985-00-1
Quantité
5 mg
Cible
TAG Degradation Platforms
Formule moléculaire
C46H39F2N9O7
Marque
Tocris Bioscience

aTAG 4531 is a degrader of MTH1 fusion proteins for use within the aTAG system. Comprises a ligand selective for MTH1, a linker and the cereblon-binding ligand Thalidomide (Cat. No. 0652). Induces highly potent and selective degradation of fusion proteins after a 4 h incubation (DC50 = 0.34 nM; Dmax = 93.14%). Cell-permeable. Suitable for

in vitro

and

in vivo

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-125962
Réf. fabricant18779786
Nom chimique ou matériauN-Cyclopropyl-6-(4-((4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)methyl)-1 H-1,2,3-triazol-1-yl)butyl)carbamoyl)-3-fluorophenyl)-7-fluoro-4-(phenylamino)quinoline-3-carboxamide
CAS2412985-00-1
Quantité5 mg
CibleTAG Degradation Platforms
Formule moléculaireC<sub>46</sub>H<sub>39</sub>F<sub>2</sub>N<sub>9</sub>O<sub>7</sub>
Pureté98%
Une question, une configuration particulière ?
Contactez-nous pour un devis.
Demander un devis 03 65 67 15 79

Produits similaires

Tocris Bioscience&trade;&nbsp;BAY 805

Tocris Bioscience™ BAY 805

174,94 € HT
Tocris Bioscience&trade;&nbsp;BAY 805

Tocris Bioscience™ BAY 805

174,94 € HT
Tocris Bioscience&trade;&nbsp;RNB 61

Tocris Bioscience™ RNB 61

236,49 € HT
Tocris Bioscience&trade;&nbsp;IBG3

Tocris Bioscience™ IBG3

231,10 € HT