FFA1 (GPR40) antagonist
DC 260126 is a free fatty acid receptor 1 (FFA1/GPR40) antagonist. Inhibits FFA-induced increases in intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells
in vitro
. Decreases serum insulin levels, improves insulin sensitivity and reduces the number of apoptotic pancreatic β cells in obese diabetic (
db/db
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-126036 |
| Réf. fabricant | 18709967 |
| Nom chimique ou matériau | N-(4-Butylphenyl)-4-fluorobenzenesulfonamide |
| CAS | 346692-04-4 |
| Quantité | 10 mg |
| Cible | Free Fatty Acid Receptor Antagonists |
| Formule moléculaire | C<sub>16</sub>H<sub>18</sub>FNO<sub>2</sub>S |
| Poids de la formule | 307.38 |
| Pureté | >98% |
