PE 22-28 is a potent inhibitor of potassium channel subfamily K member 2/TREK-1 (IC50 = 0.12 nM). In rodent models of ischemia PE 22-28 reduces apoptotic death of β cells, increases hippocampal neurogenesis, and reduces stroke-induced motor and cognitive defects.
Caractéristiques techniques
| Marque | Tocris Bioscience |
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| Réf. B-LABO | BL-RE-126108 |
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| Réf. fabricant | 18736085 |
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| CAS | 1801959-12-5 |
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| Quantité | 1 mg |
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| Cible | TREK 1 |
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| Formule moléculaire | C<sub>35</sub>H<sub>55</sub>N<sub>11</sub>O<sub>9</sub> |
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| Pureté | 0.95 |
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