Biotinylated-NAD+; substrate for ADP-ribosylation
Biotin-NAD+ is a provides a convenient non-isotopic alternative to radiolabeled NAD+ for determination of IC50 values for candidate PARP inhibitors and studies requiring this substrate. Biotinylated-NAD+ allows an indirect measure of PARP activity when biotin incorporation is detected using a conjugated-streptavidin detection system. Acts as a substrate for ADP-ribosylation. Can be used to label and purify biotinyl-ADP ribosylated proteins.
This product is a replacement for R&D Systems product 4670-500-01 .
131 μg is supplied as 500 μl of a 0.25 mM solution in water.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-126218 |
| Réf. fabricant | 18716376 |
| Nom chimique ou matériau | β-Nicotinamide-N6-[2-[[6-[biotinyl]amino]hexyl]amino]-2-oxoethyl]adenine dinucleotide |
| CAS | 146385-37-7 |
| Quantité | 131 μg |
| Formule moléculaire | C<sub>39</sub>H<sub>57</sub>N<sub>11</sub>O<sub>17</sub>P<sub>2</sub>S |
