Azide-functionalized Thalidomide; click cereblon ligand for PROTACs
Thalidomide 4'-oxyacetamide-alkylC4-azide is a click-activated Thalidomide (Cat.No. 0652); precursor to PROTAC® that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with an azide functional handle at a position known not to significantly affect binding to cereblon, for ready click conjugation to a linker/target protein ligand.
This product has been recently renamed. The previous name for this product was Azido-Thalidomide
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-126219 |
| Réf. fabricant | 18716806 |
| CAS | 2098488-36-7 |
| Synonyme | Azido-Thalidomide |
| Quantité | 50 mg |
| Cible | Degrader Building Blocks |
| Formule moléculaire | C<sub>19</sub>H<sub>20</sub>N<sub>6</sub>O<sub>6</sub> |
| Poids de la formule | 428.4 |
| Pureté | 98% |
