NLRP3 inflammasome inhibitor
16673-34-0 NLRP3i is a NLRP3 inflammasome inhibitor. Inhibits formation of NLRP3 inflammasome and IL-1β release in LPS and ATP-stimulated mouse macrophages and cardiomyocytes
in vitro
. Inhibits NLRP3 activation in mouse acute myocardial infarction and peritonitis models without affecting plasma glucose levels. Glyburide synthetic intermediate.
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-126350 |
| Réf. fabricant | 18729886 |
| Synonyme | JC121 |
| Quantité | 10 mg |
| Formule moléculaire | C<sub>16</sub>H<sub>17</sub>ClN<sub>2</sub>O<sub>4</sub>S |
| Poids de la formule | 368.84 |
| Type de produit | Inhibitor |
| Pureté | 98% |
