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Cytiva™ HiTrap™ Chromatography Columns with MabSelect™ VL Protein L Resin

Réf. : BL-RE-127945Réf. fabricant : 17897764 1 x 5 mL
896,00 € HT

Protein L affinity chromatography columns for capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.

Volume du lit
5 mL
Diamètre (impériale) interne
0.63 in.
Diamètre (métrique) interne
16 mm
Quantité
1 x 5 mL
Hauteur (impériale)
1 in.
Marque
Cytiva

As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.

Caractéristiques principales

  • Redesigned protein L ligand captures antibody Fabs, bispecifics, and other variants containing a kappa light chain with high binding capacity and improved alkaline stability
  • High dynamic binding capacity for efficient capture of target molecules
  • Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
  • Provides good resolution for product-related impurities in the capture of bispecific antibodies

Caractéristiques techniques

MarqueCytiva
Réf. B-LABOBL-RE-127945
Réf. fabricant17897764
Volume du lit5 mL
Diamètre (impériale) interne0.63 in.
Diamètre (métrique) interne16 mm
Quantité1 x 5 mL
Hauteur (impériale)1 in.
Hauteur (métrique)25 mm
Débit<20 mL/min.
Pression max.5 bar
Type de colonneAffinity Column
À utiliser avec (application)Antibody Affinity Chromatography

Documentation

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