Potent CXCR2 antagonist
AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both
in vitro
and
in vivo
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-128476 |
| Réf. fabricant | 18777686 |
| Type de produit | Antagonist |
| Protéines cibles | Chemokine Receptor |
| CAS | 333742-63-5 |
| Formule moléculaire | C<sub>15</sub>H<sub>14</sub>ClFN<sub>4</sub>O<sub>2</sub>S<sub>2</sub> |
| Poids de la formule | 400.88g/mol |
| Contenu et stockage | Store at -20°C |
| À utiliser avec (application) | Chemokine Receptor Antagonists |
| Quantité | 10 mg |
