Antiviral; also α-crystallin (cryAB) chaperone
25-Hydroxycholesterol is an antiviral. Stimulates expression of miR-185 microRNA which inhibits the hepatitis C virus life cycle via inhibition of cholesterol biosynthesis and virus cell membrane fusion. Also α-crystallin (cryAB) chaperone (Kd = 10.1 μM). Blocks α-crystallin aggregation and partially reverses cataract formation by binding and stabilizing soluble forms of cryAB
in vitro
and
in vivo
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-128525 |
| Réf. fabricant | 18717948 |
| Type de produit | Inhibitor |
| CAS | 2140-46-7 |
| Formule moléculaire | C<sub>27</sub>H<sub>46</sub>O<sub>2</sub> |
| Poids de la formule | 402.65 |
| Contenu et stockage | Store at -20°C |
| À utiliser avec (application) | Antiviral Compounds |
| Quantité | 10 mg |
