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R&D Systems™ Mouse DCC (NP_031857) VersaClone cDNA

Réf. : BL-RE-144516Réf. fabricant : 18796669 10 μg
1 117,68 € HT

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

Expression
mDcc
Numéro d’adhésion
NP_031857
Concentration
10 μg at 0.2 μg/μL
Formule
cDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert
4357 bp
Marque
R&D Systems

Caractéristiques principales

  • Also known as: Igdcc1; C030036D22Rik
  • DCC is a transmembrane protein that is a member of the immunoglobulin superfamily.
  • DCC is expressed on axons during development where its binding to Netrin-1 regulates axon migration and myelination. It inhibits apoptosis when bound by Netrin-1 and can induce apoptosis in the absence of ligand.
  • DCC also functions as an adhesion molecule and a tumor suppressor on intestinal epithelial cells.
  • Deficiencies in DCC function are associated with the development and metastasis of many tumors.
  • The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
  • For reasearch use only. Not for use in humans.

Caractéristiques techniques

MarqueR&D Systems
Réf. B-LABOBL-RE-144516
Réf. fabricant18796669
Expression<i>m</i>Dcc
Numéro d’adhésionNP_031857
Concentration10 μg at 0.2 μg/μL
FormulecDNA is provided in 10 mM Tris-Cl, pH 8.5
Type d’insert4357 bp
Identification génétique (Entrez)1630
Contenu et stockageStore the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
EspècesMouse
Quantité10 μg
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