"/> Tocris™ AP 20187 | B-LABO France

Tocris™ AP 20187

Réf. : BL-RE-151258Réf. fabricant : 18788946 5 mg
444,91 € HT

Chemical inducer of protein dimerization; active in vivo

Nom chimique ou matériau
2,2 '-[[2-[(Dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1 R)-3-(3,4-dimethoxyphenyl)propylidene]]] bis[1-[(2 S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate]
CAS
195514-80-8
Quantité
5 mg
Cible
Protein Dimerizers
Formule moléculaire
C82H107N5O20
Marque
Tocris

AP 20187 is a chemical inducer of dimerization (CID) for use in FKBP fusion protein systems. Induces apoptosis in cells expressing fusion proteins consisting of FKBPF36V and the intracellular domain of the Fas receptor, Fas-associated death domain (FADD) or a caspase. Selective for FKBPF36V-Fas fusion proteins over wild-type FKBP. Induces apoptosis of senescent cells expressing caspase-8-FKBP fusion proteins under the control of an

Ink4a

promoter. Active

.

Caractéristiques techniques

MarqueTocris
Réf. B-LABOBL-RE-151258
Réf. fabricant18788946
Nom chimique ou matériau2,2 '-[[2-[(Dimethylamino)methyl]-1,3-propanediyl]bis[imino(2-oxo-2,1-ethanediyl)oxy-3,1-phenylene[(1 R)-3-(3,4-dimethoxyphenyl)propylidene]]] bis[1-[(2 S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate]
CAS195514-80-8
Quantité5 mg
CibleProtein Dimerizers
Formule moléculaireC<sub>82</sub>H<sub>107</sub>N<sub>5</sub>O<sub>20</sub>
Pureté0.98
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