Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside
EIDD 1931 is a viral RNA-dependent RNA polymerase (RdRP) inhibitor and broad spectrum antiviral nucleotide. Inhibits replication of a range of RNA viruses including influenza, Ebola, HCV, and human and zoonotic coronaviruses (IC50 values are 0.15 and 0.3 μM for inhibition of MERS-CoV and SARS-CoV-2 replication
in vitro
). Increases mutation rates and induces lethal mutagenesis in viral RNA. Also inhibits replication of mouse hepatitis virus with mutations conferring resistance to remdesivir (Cat. No. 7226).
| Marque | Tocris |
|---|---|
| Réf. B-LABO | BL-RE-151324 |
| Réf. fabricant | 18745976 |
| Nom chimique ou matériau | N-Hydroxycytidine |
| CAS | 3258-02-4. |
| Quantité | 5 mg |
| Cible | RNA/DNA Polymerase Inhibitors |
| Formule moléculaire | C<sub>9</sub>H<sub>13</sub>N<sub>3</sub>O<sub>6</sub> |
| Pureté | 0.98 |
