PROTAC comprised of a highly promiscuous kinase inhibitor conjugated to the cereblon E3 ubiquitin ligase ligand, pomalidomide (Cat. No. 6302). Degrades a range of kinases in MOLT-4 and MOLM-14 cell lines.
Negative control TL 13-27 (Cat. No. 6525) is also available.
Degrader (PROTAC®) comprised of a highly promiscuous kinase inhibitor conjugated to the cereblon E3 ubiquitin ligase ligand, pomalidomide (Cat. No. 6302). Degrades a range of kinases in MOLT-4 and MOLM-14 cell lines.
Negative control TL 13-27 (Cat. No. 6525) is also available.
Caractéristiques techniques
| Marque | Tocris Bioscience |
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| Réf. B-LABO | BL-RE-151430 |
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| Réf. fabricant | 18709406 |
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| Nom chimique ou matériau | N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamide |
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| CAS | 2250025-88-6 |
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| Quantité | 5 mg |
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| Formule moléculaire | C<sub>44</sub>H<sub>51</sub>ClN<sub>10</sub>O<sub>9</sub>S |
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| Poids de la formule | 931.46 |
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| Pureté | 98% |
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