Oseltamivir phosphate is a viral neuraminidase inhibitor prodrug; metabolized to GS 4071. Metabolite exhibits potent inhibition of neuraminidase from multiple influenza strains (IC50 values range from 0.3 to 2 nM). Inhibits cellular effects of influenza infection
in vitro
(IC50 values range from 0.6 to 150 nM). Displays highest potency against H1N1 and H3N2 influenza A strains. Inhibits H1N1 influenza infection in mice.
Caractéristiques techniques
| Marque | Tocris |
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| Réf. B-LABO | BL-RE-151531 |
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| Réf. fabricant | 18735506 |
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| Nom chimique ou matériau | Ethyl (3 R,4 R,5 S)-4-Acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate phosphate |
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| CAS | 204255-11-8 |
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| Quantité | 100 mg |
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| Cible | Hydrolase Inhibitors |
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| Formule moléculaire | C<sub>16</sub>H<sub>28</sub>N<sub>2</sub>O<sub>4</sub>.H<sub>3</sub>PO<sub>4</sub> |
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| Pureté | 0.98 |
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