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Tocris Bioscience™ (+)-JQ1 bump, acid functionalized

Réf. : BL-RE-151572Réf. fabricant : 18005542 50 mg
2 544,23 € HT

Functionalized BET bromodomain ligand; precursor for Tag Degraders

Nom chimique ou matériau
(R)-2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoic acid
CAS
2421153-77-5
Quantité
50 mg
Cible
BRD4
Formule moléculaire
C21H21ClN4O2S
Marque
Tocris Bioscience

(+)-JQ1 bump, acid functionalized is a BET bromodomain binding analog of (+)-JQ1 (Cat. No. 4499) that selectively binds single point mutant form of Brd4 (Brd4BD2 L387A). Functionalized with a carboxylic acid group to enable onward chemistry. The position of the carboxylic acid group represents an 'exit vector' allowing modification without interfering with compound binding ability.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-151572
Réf. fabricant18005542
Nom chimique ou matériau(R)-2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoic acid
CAS2421153-77-5
Quantité50 mg
CibleBRD4
Formule moléculaireC<sub>21</sub>H<sub>21</sub>ClN<sub>4</sub>O<sub>2</sub>S
Pureté98%
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