"/> Tocris Bioscience™ SGC 6870 | B-LABO France

Tocris Bioscience™ SGC 6870

Réf. : BL-RE-151621Réf. fabricant : 18065432 5 mg
242,36 € HT

Potent and selective PRMT6 allosteric inhibitor

Nom chimique ou matériau
(R)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS
2561471-27-8
Quantité
5 mg
Cible
Protein Arginine Methyltransferase Inhibitors
Formule moléculaire
C23H21BrN2O2S
Marque
Tocris Bioscience

SGC 6870 is a potent and selective protein arginine methyltransferase 6 (PRMT6) allosteric inhibitor (IC50 = 77 nM). Exhibits selectivity over all other PRMTs and 23 methyltransferases. In HEK293T cells overexpressing PRMT6, inhibits asymmetric dimethylation of H3R2 (IC50 = 0.8 μM) Negative control SGC 6870N (Cat. No. 7184) also available.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-151621
Réf. fabricant18065432
Nom chimique ou matériau(R)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS2561471-27-8
Quantité5 mg
CibleProtein Arginine Methyltransferase Inhibitors
Formule moléculaireC<sub>23</sub>H<sub>21</sub>BrN<sub>2</sub>O<sub>2</sub>S
Pureté0.98
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