Selective LXR inverse agonist
SR 9243 is a selective LXR inverse agonist. Exhibits no significant activity at other nuclear receptors at maximally effective concentration. Inhibits the Warburg effect and lipogenesis by down-regulation of LXR-mediated gene expression. Selectively reduces cell viability and induces apoptosis in cancer cell lines
in vitro
. Suppresses hepatic steatosis and inhibits growth of tumor xenografts in mice.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-152017 |
| Réf. fabricant | 18797536 |
| Couleur | White |
| Type de produit | Inhibitor |
| CAS | 1613028-81-1 |
| Formule moléculaire | C<sub>31</sub>H<sub>32</sub>BrNO<sub>4</sub>S<sub>2</sub> |
| Poids de la formule | 626.62g/mol |
| Solubilité | Soluble to 20mM in DMSO |
| Contenu et stockage | Store at 4°C |
| À utiliser avec (application) | Inhibits IL-1β |
| Quantité | 10 mg |
