Features of the MabCaptureC Affinity Matrix include:
Points forts
Main characteristics
For process development and resin screening, MabCaptureC is also available in the following formats:
- Matrix: agarose-based, epoxide activated
- Average particle size: 75 ± 10 μm
- Ligand: recombinant C domain of Protein A
- Ligand coupling method: epoxide coupling
- Binding capacity: >50 g IgG/L resin at 4.8 min residence time and 10% breakthrough
- Elution conditions: 0.1 M glycine pH 3.0, or 20–100 mM sodium citrate or acetate, pH 3.0
Caractéristiques principales
- High dynamic binding capacity for mAbs of >50 g/L at 4.8 min residence time
- Purification of mAbs and a subpopulation of scFv's and Fab fragments containing VH3 binding domains
- Clean and sanitize with standard sodium hydroxide agents for chromatography products
- Excellent scalability
- Non-animal derived
Caractéristiques techniques
| Marque | Thermo Scientific |
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| Réf. B-LABO | BL-RE-152214 |
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| Réf. fabricant | 30019889 |
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| Type de produit | Affinity Matrix |
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| Capacité de liaison | >50 g IgG/L |
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| Ligand | Engineered rProtein A |
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| Matrice | Agarose-based, epoxide-activated |
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| Granulométrie | 75 ±10 μm |
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| Cible | CH2-CH3 interface Fc-region |
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| Formule | Suspension in 20% ethanol |
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| À utiliser avec (application) | Monoclonal antibody purification |
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| Quantité | 250 mL |
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| Forme | Agarose Bead |
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