This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
Western Blotting
Caractéristiques principales
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Transfected Cell Line: 293T
Plasmid: pCMV-FCGR3A full-length
Host: Human
Theoretical MW: 32.6kDa
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Caractéristiques techniques
Marque
Abnova
Réf. B-LABO
BL-RE-160592
Réf. fabricant
16124901
Lignée cellulaire
293T
À utiliser avec (application)
Western Blot
Numéro d’ordre du gène
BC036723.1
Poids moléculaire
32.6
Plage de pH
6.8
Plasmide
pCMV-FCGR3A full-length
Test du contrôle qualité
Transient overexpression cell Lysate was tested with Anti-FCGR3A antibody (H00002214-B01) by western blotting
Quantité
100 μL
Tampon de stockage
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Espèces hôtes
Human
Contenu et stockage
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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