SLU-PP-332 is a potent and selective pan estrogen related receptor (ERR) agonist (EC50 values are 98 nM, 230 nM and 430 nM for ERRα, ERRβ and ERRγ respectively). In a mouse model of metabolic syndrome SLU-PP-332 increases energy expenditure and fatty acid oxidation, decreases fat mass, and improves insulin sensitivity. Also increases mitochondrial respiration
in vitro
.
Caractéristiques techniques
| Marque | Tocris Bioscience |
|---|
| Réf. B-LABO | BL-RE-162432 |
|---|
| Réf. fabricant | 18774384 |
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| Nom chimique ou matériau | (E)-4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide |
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| CAS | 303760-60-3 |
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| Quantité | 50 mg |
|---|
| Cible | Estrogen and Related Receptor Agonists |
|---|
| Formule moléculaire | C<sub>18</sub>H<sub>14</sub>N<sub>2</sub>O<sub>2</sub> |
|---|
| Pureté | 0.98 |
|---|
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