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Tocris Bioscience™ CST 626

Name: Tocris Bioscience™ CST 626
Brand: Tocris Bioscience
SKU: 30000663
Price: 511.87 EUR
Availability: InStock

Réf. : BL-RE-165020Réf. fabricant : 30000663 2 mg

511,87 € HT

Potent pan IAP Degrader (PROTAC™)

Nom chimique ou matériau: (2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-(3-((5-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentyl)oxy)phenoxy)-N-((R)-1,2,3,
Quantité: 2 mg
Cible: Active Degraders
Formule moléculaire: C₆₁H₈₂N₈O₉S
Pureté: 0.98
Marque: Tocris Bioscience

CST 626 is a potent IAP Degrader (PROTAC™) (DC50 values at 16 hours are 0.7 nM, 2.4 nM and 6.2 nM at XIAP, cIAP1 and cIAP2 respectively; Dmax = 90-99%). Reduces cell viability in some cell types, including SUDHL6 and MOLM13 (IC50 values are 16 nM and 21 nM respectively).

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

Caractéristiques techniques

Marque	Tocris Bioscience
Réf. B-LABO	BL-RE-165020
Réf. fabricant	30000663
Nom chimique ou matériau	(2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-(3-((5-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentyl)oxy)phenoxy)-N-((R)-1,2,3,
Quantité	2 mg
Cible	Active Degraders
Formule moléculaire	C<sub>61</sub>H<sub>82</sub>N<sub>8</sub>O<sub>9</sub>S
Pureté	0.98

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Tocris Bioscience™ CST 626

Caractéristiques techniques

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