"/> Tocris Bioscience™ MR 24 | B-LABO France

Tocris Bioscience™ MR 24

Name: Tocris Bioscience™ MR 24
Brand: Tocris Bioscience
SKU: 30067255
Price: 177.10 EUR
Availability: InStock

Réf. : BL-RE-166361Réf. fabricant : 30067255 10 mg

177,10 € HT

Potent and selective MST3 kinase binding inhibitor

Nom chimique ou matériau: 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
Quantité: 10 mg
Cible: Other Kinase Inhibitors
Formule moléculaire: C₂₆H₂₉ClN₆O₃.3HCl
Pureté: 0.98
Marque: Tocris Bioscience

MR 24 is a potent and selective MST3 kinase binding inhibitor with >10 fold selectivity over MST4 (EC50 values from NanoBRET assay are 57 nM and 583 nM for MST3 and MST4 respectively). MR 24 increases the number of cells in G1 phase of cell cycle, is non-cytotoxic and cell permeable. Shows 90% stability over 1 hour in activated liver microsomes

in vivo

Caractéristiques techniques

Marque	Tocris Bioscience
Réf. B-LABO	BL-RE-166361
Réf. fabricant	30067255
Nom chimique ou matériau	8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
Quantité	10 mg
Cible	Other Kinase Inhibitors
Formule moléculaire	C<sub>26</sub>H<sub>29</sub>ClN<sub>6</sub>O<sub>3</sub>.3HCl
Pureté	0.98

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Tocris Bioscience™ MR 24

Caractéristiques techniques

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