"/> Tocris Bioscience™ MR 24 | B-LABO France

Tocris Bioscience™ MR 24

Réf. : BL-RE-166362Réf. fabricant : 30067264 50 mg
625,25 € HT

Potent and selective MST3 kinase binding inhibitor

Nom chimique ou matériau
8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
Quantité
50 mg
Cible
Other Kinase Inhibitors
Formule moléculaire
C26H29ClN6O3.3HCl
Pureté
0.98
Marque
Tocris Bioscience

MR 24 is a potent and selective MST3 kinase binding inhibitor with >10 fold selectivity over MST4 (EC50 values from NanoBRET assay are 57 nM and 583 nM for MST3 and MST4 respectively). MR 24 increases the number of cells in G1 phase of cell cycle, is non-cytotoxic and cell permeable. Shows 90% stability over 1 hour in activated liver microsomes

in vivo

.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-166362
Réf. fabricant30067264
Nom chimique ou matériau8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride
Quantité50 mg
CibleOther Kinase Inhibitors
Formule moléculaireC<sub>26</sub>H<sub>29</sub>ClN<sub>6</sub>O<sub>3</sub>.3HCl
Pureté0.98
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