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TOKU-E™ Actinomycin D ReadyMade™ Solution

Réf. : BL-RE-167367Réf. fabricant : 30044027 10 x 1 mL · Clear to Dark orange
378,20 € HT

Actinomycin D ReadyMade™ Solution is provided as a filter-sterilized solution of Actinomycin D in DMSO.

CAS
50-76-0
Certifications/Conformité
Purity >95.0%
Nom chimique ou matériau
Actinomycin D
Couleur
Clear to Dark orange
Contenu et stockage
-20°C, Protect from light
Marque
TOKU-E

As Actinomycin can bind DNA duplexes, it can also interfere with DNA replication, although other chemicals such as hydroxyurea are better suited for use in the laboratory as inhibitors of DNA synthesis. Actinomycin D and its fluorescent derivative,7-aminoactinomycin D (7-AAD), are used as stains in microscopy and flow cytometry applications. The affinity of these stains/compounds for GC-rich regions of DNA strands makes them excellent markers for DNA. 7-AAD binds to single stranded DNA; therefore, it is a useful tool in determining apoptosis and distinguishing between living and dead cells.

Caractéristiques principales

  • CAS Number: 50-76-0
  • Molecular Formula: C62H86N12O16
  • Molecular Weight: 1255.42 g/mol
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Streptomyces sp.
  • Spectrum: Actinomycin D has an inhibitory effect on Gram-positive, Gram-negative bacteria and some fungi. However, its toxicity precludes its use for infectious diseases
  • Mechanism of Action: Actinomycin is a cyclic polypeptide-containing antibiotic that binds to DNA and inhibits RNA polymerase activity

Caractéristiques techniques

MarqueTOKU-E
Réf. B-LABOBL-RE-167367
Réf. fabricant30044027
CAS50-76-0
Certifications/ConformitéPurity >95.0%
Nom chimique ou matériauActinomycin D
CouleurClear to Dark orange
Contenu et stockage-20°C, Protect from light
Concentration2.0 to 2.1 mg/mL
FormeLiquid
Type de produitAntibiotic
StérilitéSterile
Sterilization MethodSterile-filtered
Avec additifsNone
Sans additifNone
FormuleLiquid, 0.2% in Dimethyl Sulfoxide
À utiliser avec (application)Microbiology, Plant Biology, Eucaryotic Cell Culture and Cancer Applications
Qualité de fabrication1 mL
Gamme de produitsReadyMade™ Solutions
Pureté ou qualité>95.0%
Quantité10 x 1 mL
Conditions d’expéditionIce Pack
SourceStreptomyces sp.
EspècesBacteria
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