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TOKU-E™ Timentin ReadyMade™ Solution | B-LABO France
TOKU-E™ Timentin ReadyMade™ Solution
Réf. : BL-RE-167368Réf. fabricant : 30044052 10 x 1 mL · Colorless
84,19 € HT
Timentin ReadyMade™ Solution is provided as a sterile-filtered solution of Timentin (Ticarcillin Disodium with Clavulanate Potassium 15:1) in water.
Nom chimique ou matériau
Ticarcillin Disodium with Clavulanate Potassium 15:1
Forme physique
Liquid
CAS
116876-37-0
Source
Semi-synthetic
Conditionnement
2 mL plastic vial
Marque
TOKU-E
Caractéristiques principales
CAS Number: 116876-37-0
Molecular Formula: C15H14N2Na2O6S2 / C8H8KNO5
Molecular Weight: 665.64 g/mol (combined)
Storage Conditions: -20°C
Form: Liquid
Source: Semi-synthetic
Spectrum: Timentin is broad-spectrum and has activity against Gram-negative cocci other than enterococci and methicillin-resistant staphylococci; Enterobacteriaceae, including drug-resistant strains; and anaerobes
Mechanism of Action: Timentin interferes with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Clavulanic acid is a 'suicide' or 'mechanism based' β-lactamase inhibitor. Clavulanic acid contains a β-lactam ring that binds strongly to β-lactamase at or near its activation site, thereby permanently inhibiting enzymatic activity. This action protects other beta-lactam antibiotics (penicillins, cephalosporins, etc.) from β-lactamase catalysis, thereby enhancing their antibacterial activity
Caractéristiques techniques
Marque
TOKU-E
Réf. B-LABO
BL-RE-167368
Réf. fabricant
30044052
Nom chimique ou matériau
Ticarcillin Disodium with Clavulanate Potassium 15:1
