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TOKU-E™ Nystatin ReadyMade™ Solution | B-LABO France
TOKU-E™ Nystatin ReadyMade™ Solution
Réf. : BL-RE-167901Réf. fabricant : 30044042 10 x 1 mL · Colorless
407,33 € HT
Nystatin ReadyMade™ Solution is provided as a sterile-filtered solution of Nystatin in water.
CAS
1400-61-9
Nom chimique ou matériau
Nystatin A1
Couleur
Colorless
Contenu et stockage
-20°C, Protect from light
Description
Nystatin ReadyMade™ Solution 20,000 to 40,000 units/mol in water
Marque
TOKU-E
Caractéristiques principales
CAS Number: 1400-61-9
Molecular Formula: C47H75NO17
Molecular Weight: 926.09 g/mol
Storage Conditions: -20°C, Protect from light
Form: Liquid
Source: Streptomyces noursei and Streptomyces aureus
Spectrum: Nystatin primarily targets fungi, yeasts, and mold. It is active against Candida species, but, in vitro, some species such as C. tropicalis can develop resistance. It is either fungistatic or fungicidal depending on the concentration of Nystatin, the pH of the medium, and the nature of the infecting organism. It has a slightly narrower spectrum than Amphotericin B
Mechanism of Action: Nystatin binds ergosterol in the fungal cell membrane forming pores and increasing permeability. It is a channel-forming ionophore, meaning it forms a membrane-spanning pore in the fungal plasma membrane. The altered permeability is toxic to the fungi leading to growth inhibition or death. It has a similar mechanism to Amphotericin B. It is not active against bacteria since they do not contain sterols in their cell membrane
