TOKU-E™ Streptomycin ReadyMade™ Solution | B-LABO France
TOKU-E™ Streptomycin ReadyMade™ Solution
Réf. : BL-RE-167910Réf. fabricant : 30044034 10 x 1 mL · Colorless
97,14 € HT
Streptomycin ReadyMade™ Solution is provided as a sterile-filtered solution of Streptomycin Sulfate in water.
Nom chimique ou matériau
Streptomycin Sulfate
Forme physique
Liquid
CAS
3810-74-0
Source
Streptomyces griseus
Conditionnement
2 mL plastic vial
Marque
TOKU-E
Caractéristiques principales
CAS Number: 3810-74-0
Molecular Formula: C21H39N7O12 · 1.5 H2SO4
Molecular Weight: 728.69 g/mol
Storage Conditions: -20°C
Form: Liquid
Source: Streptomyces griseus
Spectrum: Streptomycin Sulfate is highly active against Gram-negative and mycobacterium, and less active against Gram-positive bacteria. Streptomycin Sulfate has been found to be effective against certain β-lactam sensitive vancomycin-resistant Enterococcus (VRE) species; a glycopeptide antibiotic resistant 'superbug'. It is also active against mycobacteria
Mechanism of Action: Streptomycin is a protein synthesis inhibitor. It binds to the small 16S rRNA of the 30S subunit of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This leads to codon misreading, eventual inhibition of protein synthesis and ultimately death of microbial cells through mechanisms that are still not understood. Speculation on this mechanism indicates that the binding of the molecule to the 30S subunit interferes with 50S subunit association with the mRNA strand. This results in an unstable ribosomal-mRNA complex, leading to a frameshift mutation and defective protein synthesis and eventually to cell death