ELISA
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
| Marque | Invitrogen |
|---|---|
| Réf. B-LABO | BL-RE-177223 |
| Réf. fabricant | 17869075 |
| Numéro d’adhésion | O15263 |
| Plage de dosage | Lot-specific |
| Sensibilité du dosage | Lot-specific |
| Conjugué | Biotine |
| Type de produit | ELISA |
| À utiliser avec (équipement) | Lecteur de microplaques colorimétriques |
| Identification génétique (Entrez) | 1673 |
| Symbole de gène(s) | DEFB4A |
| Contenus des kits | Capture Antibody, Detection Antibody, Protein Standard, HRP-conjugate |
| Marqueur ou colorant | HRP |
| Quantité | 10 x 96 tests |
| État réglementaire | RUO |
| Conditions de stockage | Refer to product documentation for component specific storage temperature. |
| Cible | beta-2 Defensin |
| Heure du test | 1 h 45 min |
| Durée totale du dosage | 24 h 30 min |
