"/> Tocris Bioscience™ JP-2-196 alkyne | B-LABO France

Tocris Bioscience™ JP-2-196 alkyne

Réf. : BL-RE-178142Réf. fabricant : 30281234 50 mg
385,52 € HT

RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).

Nom chimique ou matériau
1-(4-Methoxyphenyl)-4-[4-(2-propyn-1-yl)-1-piperazinyl]-2-butene-1,4-dione
CAS
2901113-25-3
Quantité
50 mg
Cible
Molecular Glues
Formule moléculaire
C18H20N2O3
Marque
Tocris Bioscience

JP-2-196 alkyne is a covalent RNF126 chemical handle that binds to several other RING E3 ubiquitin ligases including RNF14, RNF40, RNF219, MID2, and LRSAM1. By facilitating E3 ligase recruitment, JP-2-196 alkyne induces proteasomal degradation of diverse target proteins. It serves as a modular scaffold for the design and synthesis of molecular glue degraders. JP-2-196 alkyne is an alkyne functionalized version of JP-2-196 (Cat. No. 8046).

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-178142
Réf. fabricant30281234
Nom chimique ou matériau1-(4-Methoxyphenyl)-4-[4-(2-propyn-1-yl)-1-piperazinyl]-2-butene-1,4-dione
CAS2901113-25-3
Quantité50 mg
CibleMolecular Glues
Formule moléculaireC18H20N2O3
Pureté0.95
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