BAY 805 is a potent and selective inhibitor of USP21 (IC50 = 6 nM, Kd = 2.2 nM). BAY 805 induces NF-κB activation (EC50= 17 nM in a cell-based reporter assay).
- Nom chimique ou matériau
- N-[(1R)-1-[[[5-[(4-Cyanophenyl)methyl]-1,3,4-thiadiazol-2-yl]amino]carbonyl]-3-methylbutyl]-1-(trifluoromethyl)cyclohexanecarboxamide
- CAS
- 2925481-88-3
- Cible
- Deubiquitinating Enzyme Inhibitors
- Formule moléculaire
- C24H28F3N5O2S
- Pureté
- 0.98
