Sulfate de polymixine B, réactif de culture cellulaire, Thermo Scientific Chemicals
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Utilisé comme agent antibactérien pour prévenir la contamination. Le sulfate de polymyxine B est recommandé pour une utilisation dans des applications de culture cellulaire à 50 mg/l.
In cell culture, polymyxin B sulfate is used as an antibacterial agent to prevent contamination. Polymyxin B sulfate is recommended for use in cell culture applications at 50 mg/L. It is used as a lipid A binding agent that induces pore formation in cell membranes and as immobilized (substrate bound) agent for removal of endotoxins.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Points forts
General Description
• Polymixin B sulfate is a mixture of B1 and B2 polypeptides obtained from different strains of Bacillus polymyxa, with antibacterial activity against gram-negative bacteria. It does not exhibit activity against fungi and gram-positive organisms
• This compound inhibits Ca2+ dependent PKC (protein kinase C)
Application
• Polymixin B sulfate targets BAC-1.2F5 murine macrophages as an LPS (lipopolysaccharide) inhibitor
• In in vitro research, this compound is used to prevent bacterial contamination of cell cultures
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