STEMCELL Technologies G418
234,90 € HT
Antibiotic for selecting transfected mammalian cells
- CAS
- 108321-42-2
- Quantité
- 250 mg
- Marque
- STEMCELL Technologies
Caractéristiques principales
- Antibiotic G418 is an aminoglycoside related to gentamicin and is toxic to bacteria, yeast, higher plants, mammalian cells, protozoans, and helminths
- G418 binds to 80S ribosomes in prokaryotic and eukaryotic cells and inhibits protein synthesis, resulting in cell death
- Resistance to the antibiotic is conferred by aminoglycoside-3-phosphotransferase
- Vectors containing the G418 resistance gene (neo) are commonly used for transfecting eukaryotic cells, with selection of transfected cells achieved by culturing them in the presence of G418
- Cells may exhibit variable resistance to the antibiotic and can take up to a week to die
- The G418 antibiotic is suitable for use in cell culture for the selection and maintenance of G418-resistant clones when using ClonaCell™-TCS Medium (Catalog #03814), ClonaCell™-CHO CD Medium (Catalog #03815), ClonaCell™-CHO ACF Medium (Catalog #03816), ClonaCell™CHO CD Liquid Medium (Catalog #03817), or other cell culture media
Caractéristiques techniques
| Marque | STEMCELL Technologies |
|---|---|
| Réf. B-LABO | BL-RE-032781 |
| Réf. fabricant | 17120002 |
| CAS | 108321-42-2 |
| Quantité | 250 mg |
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