Used for SDS-PAGE
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq]
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-056549 |
| Réf. fabricant | 16018096 |
| Concentration | 8.3 mg/mL |
| À utiliser avec (application) | SDS-PAGE |
| Formule | In 0.05M Tris-HCl, 0.1M NaCl, pH 7.4 |
| Identification génétique (Entrez) | 462 |
| Poids moléculaire | 58kDa |
| Nom | SERPINC1 (Human) Native Protein |
| Méthode de préparation | Native protein purified from human plasma |
| Méthode de purification | Multi-step chromatography |
| Quantité | 1 mg |
| Conditions de stockage | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| État réglementaire | RUO |
| Alias de gène | AT3/ATIII/MGC22579 |
| Nom usuel | SERPINC1 |
| Symbole de gène(s) | SERPINC1 |
| Espèces | Human |
| Marqueur de protéine | None |
| Système d’expression | Native protein purified from human plasma |
| Forme | Liquid |
| Pureté ou qualité | >98% by SDS-PAGE |
